Bride-to-be Claire, her sister Leslie, fun-loving Zoe, and quirky new friend Janet set off to Las Vegas for a one-night bachelorette party that turns out to be more than they bargained for. A series of unexpected adventures rip them from the glitz and glamour of the Las Vegas strip and places them smack dab in Vegas' seedy underbelly. Determined to keep their bachelorette party dreams alive, the girls band together and embark on the wildest night in bachelorette party history. Fueled by sex and booze, this raunchy, riotously hilarious, out-of-control, blow-out is, for better or worse, all caught on tape. And is destined to go down as the Best Night Ever.